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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e2d0a35919c630f5d5afc5af8cec27d2a051cb4a6a0bb055c6a8370e24ddad' 
  AND token = 'WOTghN0O/UcaLFEgSWeENxINeut4ABtoHEZzx+1wA4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}