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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e61e2a642601c1e0ff1355fdd5e67d9a20df17d518530adb71932d0d6bce18a' 
  AND token = 'an3hhLm917X3w/RBIhT6YWAZbLqiOG1AB/auVZe7emo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}