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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3744026181c6802bca375d52224fa5bb850fd18f88886c09a9319e71eb1e51b' 
  AND token = '9pQ0UIqGQ0rwzTU8N59DOGNhkTFvdC/OOdsDVdJlBi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}