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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b8180862b835309859ee3c595caec34619563cb27c5d51c4e0aa5f9bf2e1d8' 
  AND token = 'Iqq3f7MgFs8xbHQKUEbY4rSZ5lIq7Fg7walIgEnd9/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}