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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c01234d11e13b3d426ae4cbc13359ee02d9bf39983809303aa10997fc5be3cc' 
  AND token = 'Pun4066ZiHZh7a1reFOS0a5EoU6wLuSlNMSxin0+lZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}