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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63ed239b2ab39004a7f1039d92a3c787828f4c9da0c8d32e0a9c79e26bcc8a8a' 
  AND token = 'CZmdfTbdueSIJ3lk4TrRC/CYVTsuejXxlXY8mjDJuL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}