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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463e9c7b6fef519e4a205fc44400be82c49b62e6a321fe141a72d7ac13d2fbba' 
  AND token = 'kWB7heR6gxYprFTdODm/qubkl3FSKyBOorZBpb9Blvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}