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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03d1fd38c186d398d3ff36066faa7234e9c31f27e1781f7293a1b796d433fa50' 
  AND token = 'aeZvGxRwu6NM9cjBKZOKT8sKoaU5LCIZbZBxRrhXF9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}