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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c4cf0b68b5a08aa312a1b8f8f90e4b28a193579e5da06eaa503eba0a46a067' 
  AND token = 'HUBgJ89nlddWFbArbC/5NpSj+Z/ynV8jDMS8gcrD96Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}