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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c781f8cf4699b1686fb50263f07df66f9b65554960c88eaba3b77ee9cf116ddf' 
  AND token = 'pXlELD0oQkZ5BxCGPDzV94EJIE/zcx3QyWh47DmHdAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}