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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735e7863ed5639d2ca78de7c94e1d76f7239b8c6568f714e3fb75287e4981293' 
  AND token = 'i57H5r0ZWnDoyNoybzJiHZVEBHhmwaJ+GACeOtCspS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}