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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fb4952c790e627458f51b4afd7f7bea1d9457d829f66e5141e5869f5637c33b' 
  AND token = '7+GY8R0l9KexL/PQ7wA5c3jWgh1YD5sq7fNTRU9UQio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}