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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd33f6bf831e6e0a617777bb7d64c7839b956864e277fa5b2d540fbbd48ac43' 
  AND token = '++B7YNlXSL5EPL57jsk8F9cpJky/j4/A3SWC79vXols=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}