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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6146738c8094f7c4ba727df481a58372921c7f7d76ac50effa1a5d10013ff5' 
  AND token = 'N2kCs7+DRZavDRxjzVDqm1ENKUN1adI7RS6pUeH3te4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}