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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25af9a55fc2ede74ed386d4c1dfa2e62c74fff2aea7afd183ce9a8f01b5d624' 
  AND token = 'CrhCsy09xT4qX/gNjM9/gvr3lallZPAeIAZNpJdLAyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}