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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f59213007e080aaa2111a1733e8417308e5aae2b1db7a6c8bc7cbf844a4257a' 
  AND token = 'y6c4D/VAv3bMItXr4HR25W9UrYEt/Zo0Z7wyb+ehUPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}