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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259b9eda35122f7796df0e8d5e63e96c6e8a9e7e8329405a0e31f31f52c51ed5' 
  AND token = 'hUdo9Q5W9zyp63dGeY/KyDNzs61mnCzcWvXGpsL4bew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}