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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '175fe9e548fa21dd8a8f80082d3ad9793d91f62e2d2c25d5fec33852dc8bd300' 
  AND token = 'ebKK8iX6wlEM2xZcDEstXYX6Lrc/ZvXSJVEg1DX2RWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}