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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a7fcfcbc0c7f3425b4ce66453465381686b187a2305946104f5abd736be7ee7' 
  AND token = 'IlMQ5OE45S65bKJWqqYTzlZ6ClO+Htsb/5CfMLJ27iE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}