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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5bcbc0d62ac5d508a57bbe2d86b8aa221763625ff017881075d43f8a68c2a06' 
  AND token = 'x1bvV9gD5b/gnMWvqV1MuWiHYmb/Z38I0UQuqTlJlFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}