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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff498399b6492cb50d9242d5e5d71143ee0be81e4e253f6362e2bc30ca61f394' 
  AND token = '51r97kDk2xSJh9HSrQ301lhHkDZdOI42ElKcBJn+DGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}