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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e844dd280d558ea130ef0d7842213055d129c06630ddcb42f7e193655ad6e646' 
  AND token = 'qMbvaqTdVYhGgHbn5coylDAv3ws2pWxF6yzMJlO05hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}