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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f6d238467ee0fe30c00cb106f26aaa33411b02e50175bb001d9b30186f2a47f' 
  AND token = 'epuDM9TTaUIYSnm4VQzkoKkLY15R9yhkJVErxHiYFQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}