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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f3593d85989732eb86e7c79244d740b8d4d427966705c4eebea16fc96f9daaa' 
  AND token = 'k1DUim0TvffINImL4NY4lwgq9JuLPZyOYoQsr7Mf3Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}