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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '684dc1754399ec2ea562713b25ceba5dc8679c9e702658e2afef7b3855e08be7' 
  AND token = 'Jwm3Vy751LN+GVPcrdFDgy46T/eYCS17bXos65f2X58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}