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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '564ca718a7f4a0ef7761ac8f540b0a196e2fe21dc02ffc802ecab7a2b40524ee' 
  AND token = '2y2axsFluwlwPzxN3MTAIHGNMa121St+MqplguqvmkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}