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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b165e0046eaab7a2f64f0c8bb814c1a2b3bfde14ef67600a1c513c359a22f73' 
  AND token = 'hJv41QRfS7P/7c3afY/IsPsIhmJM1N4W8DL2vIkV7NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}