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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0849b2965c4977d372788cf18e75a9fbec2507d626ba39636a5e22ef39da9df' 
  AND token = 'BmduzV3USuL5sIlK6or9pNAA6e3xpb8Hy6p4PZi9igk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}