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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265c2cccb1854481953f051d820dfc9ef0dd5c974914295b8c31fc80afbba581' 
  AND token = 'Z8yCItehBQ+Vnk/b9/Cw9kTA0kjNPPDcG9J85fvCm+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}