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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e4e33278c5ba240d5b9b67932260289cd9c322b5f0fcb31d79c1b8d51d7313' 
  AND token = '1zPevTZu14qnI+JobQSliVybsZvWSue59jK7lKcTibc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}