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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c2888a4c6a5031c96547962158ad0f276c1f76a4f9e19588a2e880e4d01639' 
  AND token = 'OovZVDXDRh+v+oaoU7Wzm2U5skAoV4o2ZQ9lx2TAJ9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}