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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fa76400a43cc1bc0a2731e26057e5e1e915f274c70288899c3efa67de07d2f9' 
  AND token = '8FGeeqg5L8Wsy/3fMUYrf4gtcnkWS1KBEDzJpDC1YKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}