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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8e1d15f00c2d38466e944f352db096096bc3c3d580d4e19faf43036dcec448' 
  AND token = 'LOWM4r3BkWGy7LLGM09jkrDzfWp5APSKVZ6TDz5y50w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}