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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a68a42c64acb955f4f139ff32e1ce508beedc94d8691e8fff93cfe22bd54516c' 
  AND token = 'OtO8FimgbQNfFd1iZtwu86CDkd351gZeQZRIO/AZPdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}