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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5728c7797f2d04612f8c56ff49fa2ebdbdc61b0e0675453a4cf982c0c72f5f3' 
  AND token = '+sAxM9vkbpj9UHIB95lUNbLQlM2J5NDYLm68V8I8IB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}