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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14f2a4b8e0c7f19daa7aa3d54e90c61913a882ccd6f0273c9bef6745a7d9b5c5' 
  AND token = 'VbCACW9RwgH0WEDcWHtHlOAMUzzUabcD2dV7TIFi/OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}