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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc1ae09191e1a3fce830cb4ad7f159da8b0bac601a443b7639bd8f64d803d95e' 
  AND token = 'NQzzai43lOGieY/H09zNozRGS6+0IqhdC0ky1tpHbtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}