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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '203397b8b20279f70f9e6c65e199f535625dc8e6007253d9c6614a574e81cf75' 
  AND token = 'duRqAswqqygt0TYdPPcGSfe+N6dPH57/kfE3xDtL7eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}