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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2469aedf83df4b415a784bb27a3e8da2f5e1d55250202e8b209b348a7eed659c' 
  AND token = 'MtXk5nF4LIT1z74+VFc1AoPTOOxuqoFWclMKL9VQuVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}