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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2728f6d9c103d4f4882001d1cc1354629f8a92c6f25ffcdbd80f6f065f2eeaaa' 
  AND token = 'oKRIsm2CYbCrW/AdYie4YWKLW6iNQ15mnr6Tctm2O2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}