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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066d19b9b56b0e2895f84e3a5b6243d0b840be8da4e3ecebbcb3db52779f1fda' 
  AND token = 'jms27/2RDc/uo3pAOAat0eRMKxdnhvX2DjgUxqDcHF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}