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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4ab22117b0c707c33a05cfed293ac5539028863f7aedfcb52964d7aadd6bc7' 
  AND token = 'cMk1q9e+HYyUK/D5JxBE7T3buO0KFwvTtrZtqWGs2kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}