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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d478429a3fb2e8b351942baea42d8c7623ae88a5bd0d34148a238bcfa56f7d1' 
  AND token = '8rZq8P+2XsHoLZEOlwRd4VvA5JStEoJIbPSgO8gY2kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}