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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e8a3e390872dfa246671fa7c18e26b49d8d6804789ae7f9e7cf3a450779d57' 
  AND token = 's09k9MiWChxDuBMpVKGg7SzDjEsIfdjkkzhnIOhc/JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}