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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5df76b3d4180a50fd2bf85f195fbab4e86b86bd621af3dea9a54035806aba5e' 
  AND token = 'lIVGUh+2d/f1fbOcfGP8OchAFKGW+ZkfZYuKNfVwXsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}