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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8404b06cf47ed6e4538a3039c5397cdaaff9b73b7ac66680b7aab16f4c0e0720' 
  AND token = 'eTZtEuC34GGupELv1r+iWtUXNk/1pWiFbuqrX8YPrYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}