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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7ee36ad3f8921e903edc366d198bf847c04faac9c159998f9f72d835c5b4c8' 
  AND token = 'VG5poIG3tP+aG2xy/ZD9+SagQ1bE2k+6K8228rd4pyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}