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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bdb0719deb2d9de12f43e03a17793f1e45e7c1dce6cb467cd949519bd18c627' 
  AND token = 'cG1/EMKSftDPliLi0W4a6zVo9Y5vYPo+1CtU0HoKDOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}