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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e67554bbed90b5914066c15d78b23fccc5ca7727faf99e2ae50364a45478827' 
  AND token = 'qJc5+wew7zEzuOT0Pl5IbHS5+ibOWs8KxetYmj/uwo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}