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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b48bada98c10a9f2e9332603522df96da57eaf88b1101e42b2d9a8bc3c2ab0' 
  AND token = '0YwKKjuE9nP4JgcT/+Ep+rs1ocHEUj7I/KF1zyHOAQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}